The Surprising Truth About Long-Term Melatonin Use and Heart Health
The Surprising Truth About Long-Term Melatonin Use and Heart Health
November 5, 2025
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Overview
Here's the thing: melatonin has been a go-to for many people looking to catch some Z's. You might be wondering, though, if those nightly doses could have a long-term impact on your health. Recent research suggests that using melatonin supplements for extended periods may increase the risk of heart failure and other serious health issues [1][2]. In a study involving over 130,000 adults, those who used melatonin for at least a year were found to be at a higher risk of developing heart problems [3].
Many folks rely on melatonin, thinking it's a harmless sleep aid, but the findings raise a red flag. It turns out that while melatonin can help regulate sleep cycles, it may not be as benign as we once thought. Some studies indicate that prolonged use could lead to increased hospitalization rates for heart-related issues and even higher mortality rates among those using it regularly [4][5].
Let me break this down further: melatonin is a hormone our bodies produce naturally, signaling to us that it’s time to sleep. When taken in supplement form, it can help people falling asleep faster. However, when used long-term, it’s essential to consider how it might affect your heart health. The bottom line is that if you're relying on melatonin night after night, it might be worth discussing with your healthcare provider to weigh the risks and benefits [6][21].